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Archive for the ‘Gene interactions’ Category

ResearchBlogging.org
I learnt about epistasis in twelfth year of schooling. It was first used by Bateson to describe the masking of one allele(variant of a gene) at a locus masking another allele at a different locus. But today I see this word used in different contexts and I was really confused about its meaning, so looked on the net to find this paper describe wonderfully what I was looking for.
Cordell, H.J. (2002). Epistasis: what it means, what it doesn’t mean, and statistical methods to detect it in humans. Human Molecular Genetics, 11(20), 2463-2468. DOI: 10.1093/hmg/11.20.2463

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