Last week I blogged on the talk by Peter Fraser where he showed evidence for the existence of transcription factories. He showed pictures as follows to demonstrate the theory of transcription factory.
Fig. 1. Transcription factories are concentrated foci of active RNA polymerase. Immuno-detection of the hyper-phosphorylated form of RNAPII reveals their [...]
Archive for the ‘transcription factory’ Category
No transcription factories !!
Posted in DNA-protein interactions, RNA POlII, gene regulation, transcription, transcription factory, tagged FISH, RNA pol II, transcription, transcription factory on February 19, 2008 | Leave a Comment »
Transcription factories
Posted in DNA-protein interactions, gene regulation, transcription, transcription factory on February 7, 2008 | Leave a Comment »
Today we had a very fascinating story by Peter Fraser (from the Babraham Institute, Cambridge), suggesting that genes migrate to specialized sites called transcription factories in the nucleus for transcription. These transcription factories are nothing but discrete foci in the nucleus containing high concentrations of RNA polII(the eukaryotic polymerase responsible for transcription of protein-coding [...]
